A critical challenge at core facilities are poor quality inputs such as FFPE, liquid biopsies, ancient DNA. These inputs are highly fragmented and degraded and perform poorly on standard NGS workflows. ClaretBio’s mission is to enhance the quality of sequencing data obtained from such challenging sample types. Our flagship library preparation method SRSLY generates high complexity libraries from picogram amounts of fragmented and degraded DNA. At this webinar, you will hear from two accomplished speakers who have developed robust workflows to challenging samples – non-plasma liquid biopsies and bones to generate high quality NGS data.
THE SERIOUS TALK - 5
The Missing in Action Recovery and Identification Project at the @uwmadison is a mission to retrieve personnel killed in overseas conflicts by performing excavations and research assistance to families of the missing. In the past this has been accomplished by combining military archives with eyewitness accounts and familial records to locate probable sites for excavation and recovery. Once potential identification elements are reclaimed, a portion can be sequenced to generate a putative identification. It is common that recovered elements are not the ideal source material for DNA extraction and subsequent sequencing library assembly due to combinations of elemental exposure and scarcity of materials. To overcome this obstacle, we have been treating these as ancient DNA samples that require modern DNA extraction and library assembly methodologies. Here I will report how I have employed these techniques to advance the Recovery and Identification missio